What are electrolytes?
Minerals in the body that have an electric charge, found in blood, urine, tissues and other body fluids
What do electrolytes do?
Maintain homeostasis by balancing water content and the body’s pH level, ensure healthy function of nerves, muscles, the heart and the brain
What are electrolytes obtained from a balanced diet?
Sodium, calcium, potassium, chloride, phosphate and magnesium
What is homeostasis?
The process of keeping the internal environment of any organism/cell relatively constant and different from its external environment - required to keep it alive.
Why must a cell import some substances and export others?
To keep the concentrations of ions inside any cell at a different level from the concentrations outside
Do electrolytes carry a charge?
Yes
Which of sodium and potassium higher extracellularly?
Sodium
Can your body cope if fluid is not balanced?
Yes the body can adapt but this is not healthy
Which enzyme is produced in the kidneys in response to sympathetic stimulation and altered blood flow?
Renin
What does renin do?
Converts angiotensin to angiotensin I
How is angiotensin I converted to angiotensin II
In the lungs by angiotensin converting enzyme (ACE)
What does angiotensin II do?
Constricts blood vessels, increasing blood pressure - most important constrictor in the body
What does angiotensin II stimulate to produce the hormone aldosterone?
The adrenal cortex
What does aldosterone activate?
The pump in the distal renal tubule leading to reabsorption of Na+ and water from the urine in exchange for K+ and H+ ions
How does control of water balance work?
Increased plasma Na+ concentration causes thirst and release of antidiuretic hormone (ADH) from the posterior pituitary which increases the passive water reabsorption from renal collecting dusts
Are electrolytes important for transport?
Yes
What are the clinical features of low body sodium?
Cellular over hydration, confusion, fits
What are the clinical features of water excess?
Hypertension, cardiac failure, oedema, anorexia (patients may drink more water), nausea, muscle weakness
What are the clinical features of high body sodium?
Cellular dehydration, thirst, confusion, coma
What are the clinical features of water deficiency?
Hypotension, low pulse volume, decreased skin turgor (elasticity), peripheral vasoconstriction, tachycardia, raised plasma protein
What is the definition of dehydration?
When the body loses more fluid than it takes in
What are the early signs of dehydration?
Feeling thirsty and lightheaded, dark coloured, strong smelling urine, peeing less than usual
What are the signs of dehydration in babies?
Sunken soft spot (fontanelle) on their head, few or no tears when crying, fewer wet nappies, drowsiness. Note: body is affected even when they lose a small amount of fluid