What is osmolality and what does it measure?
The concentration of dissolved particles in blood serum - indicates the balance between body fluid and solutes helping to diagnose dehydration/euhydration/overhydration and hormone issues.
What is the normal plasma osmolality of dogs?
290-310 mOsm/kg
What is the normal plasma osmolality of cats?
290-330 mOsm/kg
What is osmolarity?
the number of particles of solute per liter of solution
What 3 substances does blood plasma contain?
Glucose, sodium, and urea
What are four examples of insensible losses?
Sweating, panting, nasal discharge, and burns
If a patient is dehydrated, will their osmolarity increase or decrease and why?
INCREASE because the amount of water in the body has decreased, leaving behind extra solutes
Increased osmolarity causes water to flow ______ of the cell, causing the cell to ______.
Out, contract
Hyperosmotic solutions
Solution whose osmolality is greater than that of plasma
Hypoosmotic solutions
Solution whose osmolality is less than that of plasma
Isoosmotic solutions
Solution whose osmolality is equal to that of plasma
What is tonicity and what is it dependent on?
The ability of a solution to initiate water movement - dependent on the presence of impermeant solutes in the solution
Name the four functions of sodium
Maintains serum osmolality, water balance, nerve impulse conduction, and muscle contraction
Sodium is regulated by what hormone system/s?
RAAS (and the kidneys)
Where is most of the body’s sodium found?
Extracellular fluid (ECF)
How is sodium measured? (2 options)
mEq/L or mmol/L
Typically, where does sodium come from?
Diet and water intake
Normal ECF concentration of sodium
140mEq/L
Normal ICF concentration of sodium
10mEq/L
Water moves ______ the concentration gradient
Along, from low osmolality to high osmolality
What is the primary effective osmole of ECF?
Sodium
What is the primary effective osmole of ICF?
Potassium
How is sodium removed from the ICF, and what is it exchanged for?
Na/K ATP pump, exchanged for potassium