Endemic typhus

Question 1

Endemic typhus (agent)

Answer 1

Ricketssia typhi

Question 2

Endemic typhus (region and vector)

Answer 2

southern US, cat and rat fleas

Question 3

Endemic typhus (clinical)

Answer 3

Incubation 8-16 days
Fever, headache, malaise
Maculopapular rash from trunk to extremities 
No eschar
Relative bradycardia

Question 4

Endemic typhus (Bill-Zinsser disease)

Answer 4

when the disease becomes exacerbated after few years

Question 5

Endemic typhus (diagnostics)

Answer 5

DIF (increased Abs), + weil-felix

Question 6

Endemic typhus (tx)

Answer 6

Doxycycline or chloramphenicol