Endo

Question 1

Newborn with salt wasting

Answer 1

CAH 21-hydroxylase def, elevated 17-Hydroxyprogesterone

Question 2

Peripheral Precocious puberty

Answer 2

Non-classic CAH (also 21-hydroxylase def w elevated 17-OH, but have enough glucocorticoid and mineralocorticoid no salt wasting)

Question 3

Workup for precocious puberty

Answer 3

Bone age
LH
GnRH stim then LH again
High LH = central, MRI
Low LH = peripheral

Question 4

Congenital hypothyroidism

Answer 4

85% dysgenesis

Also can’t make thyroxine, maternal Ab

Question 5

G6P deficiency

Answer 5

Von gierke 3-4 mo, doll like face

Question 6

DKA

Answer 6

NS BOLUS!! Next, insulin

Question 7

Pseudohypoparathyroidism

Answer 7

Resistance to PTH