Endo :D

Question 1

name some regular insulins

Answer 1

regular
toronto

Question 2

how long does it take to see the maximal effect of levothyroxine

Answer 2

4-6 weeks

Question 3

what are some symptoms of hyperthyroidism

Answer 3

tachycardia
angina
tremor
nervousness
insomnia
hyperthermia
inc intestinal motility and sweating

Question 4

what accounts for 90% of glucose reabsorption in the kidney

Answer 4

SGLT-2 inhibitor

Question 5

name a biguanides

Answer 5

metformin

Question 6

what kind of drug is sitagliptin

Answer 6

DPP-4 inhibitor

Question 7

what does metformin do

Answer 7

dec gluconeogenesis
inc uptake of glucose

Question 8

what type of drug is ezetimibe

Answer 8

cholesterol absorption inhibitor

Question 9

name an adverse effect of PCSK9 inhibitors

Answer 9

injection site reactions

Question 10

should you use HMG-CoA reductase inibiotrs when pregnatn

Answer 10

no, but idk why

Question 11

what do DPP-4 inhibitors do

Answer 11

inc incretin levels by inhibiting DPP

Question 12

name some adverse effects of insulin

Answer 12

hypoglycemia
lipohypertrophy

Question 13

how do methimazole and propylthiouracil work

Answer 13

inhibits iodination and coupling of tyrosine precursors bound to thyroglobulin

Question 14

name 4 drugs used to lower lipid levels

Answer 14

HMG-CoA reductase inhibitors
PCSK9 inhibitors
Chloesterol absorption inhibitor
Bile acid sequestrants

Question 15

what do PCSK9 inhibitors do

Answer 15

inhibit PCSK9 and decrease LDL levels

Question 16

Name the rapid insulins

Answer 16

lispro
aspart
glulisine

Question 17

name some DPP-4 inhibitors

Answer 17

sitagliptin, saxagliptin, linagliptin

Question 18

name a bile acid sequestrant

Answer 18

cholestyramine

Question 19

how do bile acid sequesterants lower cholesterol

Answer 19

they promote excretion of bile acids and the body uses cholesterol to replace the lost acids

Question 20

name some AE of propylthiouracil

Answer 20

liver injury
rash
arthralgia
hypothyroidism
agranulocytosis

Question 21

what do incretins do

Answer 21

increase release of insulin

Question 22

name a cholesterol absorption inhibitor

Answer 22

ezetimibe

Question 23

methimazole and propylthiouracil are what types of drugs

Answer 23

drugs for hyperthyroidism

Question 24

what is myositis

Answer 24

muscle inflammation
(pain plus elevated CK (less than 10x normal)

Question 25

name the long insulins

Answer 25

detemir glargine

Question 26

name 2 GLP-1 receptor agonists

Answer 26

liraglutide semaglutide

Question 27

name some HMG-CoA reductase inhibitors

Answer 27

statins :) atorvastatin rosuvastatin

Question 28

name 6 types of anti-hyperglycemic drugs

Answer 28

sulfonylureas biguanides glitazones GLP-1 receptor agonists dipeptidyl peptidase 4 inhibitors SGLT-2 inhibitors

Question 29

name an adverse effect of bile acid sequesterants

Answer 29

constipation

Question 30

name two drugs for hyperthyroidism

Answer 30

methimazole propylthiouracil

Question 31

name some adverse effects of HMG-CoA reductase inhibitors

Answer 31

GI disturbances elevation of liver enzyme tests myopathies (myalgia, myosistis, rhabdomyolysis)

Question 32

name a glitazone

Answer 32

rosiglitazone

Question 33

what are the three principal actions of thyroid hormones

Answer 33

stimulation of energy use stimulation of the heart promotion of growth and development

Question 34

what does PCSK9 do

Answer 34

it binds to LDL receptors and destroys them, preventing LDL from being taken up from the blood

Question 35

name some AE of methimazole

Answer 35

rash arthralgia hypothyroidism agranulocytosis

Question 36

gliclazide glyburide are what kind of drugs

Answer 36

sulfonylureas

Question 37

liraglutide and semaglutide are what kinds of drugs

Answer 37

GLP-1s

Question 38

name the intermediate insulin

Answer 38

nph

Question 39

what do glitazones do

Answer 39

dec insulin resistance

Question 40

name some adverse effects of SGLT2 inhibitors

Answer 40

fungal infections polyuria hypotension euglyemic diabetic ketoacidosis

Question 41

what is mylagia

Answer 41

muscle pain with normal CK plasma levels

Question 42

what drug has an enterogastrone effect

Answer 42

GLP1 agonists

Question 43

what do drugs for hyperthyroidism do

Answer 43

reduce syntehsis or release of thyroid hormones

Question 44

name a drug for hypothyroidism

Answer 44

levothyroxine

Question 45

what do GLP-1 agonists do

Answer 45

inc effect of GLP-1 and inc glucose-dependant release of insulin

Question 46

name some PCSK9 inhibitors

Answer 46

evolocumab alirocumab

Question 47

what kind of drug is cholestyramine

Answer 47

bile acid sequestrant

Question 48

rhabdomyolysis

Answer 48

muscle pain and CK over 10times normal elevated myoglobin

Question 49

what are bile acid sequestrants

Answer 49

nonabsorable resin that binds to bile acids

Question 50

what kind of drug is metformin

Answer 50

biguanides

Question 51

what do cholesterol absorption inhibitors do

Answer 51

blocks absorption of cholesterol from intestine

Question 52

whats an adverse effect of rosiglitazone

Answer 52

retention of fluid HF

Question 53

what is the half life of levothyroxine

Answer 53

7 days

Question 54

what do dipeptidyl peptidase inhibitors do

Answer 54

inactivates incretin hormones

Question 55

how do sulfonylureas work

Answer 55

promote inuslin secretion by the pancreas

Question 56

name 2 sulfonylureas

Answer 56

gliclazide glyburide

Question 57

what does propylthiouracil do

Answer 57

inhibits peripheral activation of T4 to T3

Question 58

what kind of drug is rosiglitazone

Answer 58

glitazone

Question 59

name some adverse effects of GLP-1 agonists

Answer 59

decreased appetite thyroid cancer risk

Question 60

name some SGLT-2 inhibitors

Answer 60

canagliflozin empagliflozin dapaglifozin

Question 61

evolocumab and alirocumab are what kinds of drugs

Answer 61

PCSK9 inhibitors