What hallmark s/s will you see in Addisons
Low sodium Low sugar High K, Ca Low fluid Decr bp Wt loss
What other s/s will you see in Addisons
Muscle weakness
Salt craving
Bronzing coloration of the skin
What is the tx for Addisons
Give steroids
S/s of cushings
High sodium High sugar Low k, ca Increase fluid Increase BP Wt gain
Overuse of steroids can cause what
Cushings
Other hallmark s/s of cushings
Moon face Buffalo hump Truncal obesity Skinny arms/legs (muscle atrophy) Osteoporosis Poor wound healing Immunosuppressive (from the steroids) Purple striae around abdomen
Tx for cushings
Find underlying and treat
What med is a steroid inhibitor
Citadil
S/s of DI
Dry and salty (hypernatremic) Dehydrated (hypovolemic) Dilute urine- decr u specific gravity and osmolality Hypotension Incr hr Wt loss Hemoconcentration
What meds are given to treat DI
Desmopressin
Vasopressin
S/s of SIADH
Hypervolemic Hyponatremia Urine concentrated- incr specific gravity, osmo Oliguria Incr BP JVD Hemodilution
Tx for SIADH
Loop diuretics
Hypertonic NS
Declomycin
Conivaptan
What is declomycin and what is it used for
Antagonizes ADH in nephrons
What is conivaptan
A vasopressin antagonist
What is done for an addisonian crisis
Fluids Glucose IV Possibly kayexalate Steroids *** get EKG for incr k***
Abrupt discontinuation of steroids can cause what?
ADDISONS