Group of disorders caused by defect in 1 or more of enzymes required for cortisol synthesis.
Defects lead to overproduction of precursors in pathway and to excessive amounts of ACTH
Congenital adrenal hyperplasia
Can have adrenal crisis with any stressor, including illness or surgery
Congenital adrenal hyperplasia
Treatment for adrenal crisis
Immediate glucocorticoid administration at 2-3 times the maintenance dose