endocrine problems: causes

Question 1

• Destruction of insulin producing cells (IDDM)
• Destruction due to
- genetic factors
- chronic relapsing pancreatitis
- immune-mediated destruction
- accumulation of amyloid in islets of Langerhans
- virus infections
• Decreased tissue response to insulin (NIDDM)
- obesity
- prolonged glucocorticoid administration

Answer 1

Diabetes Mellitus

Question 2

• Destruction of thyroid hormone producing cells

• Autoimmune lymphocytic thyroiditis
• Idiopathic atrophy of thyroid gland

Answer 2

Hypothyroidism

Question 3

Tumor of the thyroid gland

- thyroid adenoma

Answer 3

Hyperthyroidism

Question 4

• Pituitary gland tumor
• Adrenal gland tumor
• Adrenal gland hyperplasia

Answer 4

Hyperadrenocorticism