- Hormones are:
a) Products of endocrine gland secretion
b) Mediators of inflammatory process
c) By-products of tissue metabolism
d) Product of exocrine gland secretion
a) Products of endocrine gland secretion
- Select an endocrine drug which is an amino acid derivative:
a) Insulin
b) Hydrocortisone
c) Calcitonin
d) Thyroxine
d) Thyroxine
- Select an endocrine drug which is a peptide derivative:
a) Oxytocin
b) Prednisolone
c) Nandrolone
d) Progesterone
a) Oxytocin
- Select an endocrine drug which is a steroidal derivative:
a) Gonadorelin
b) Insulin
c) Levothyroxine
d) Hydrocortisone
d) Hydrocortisone
- Hormone analogues are:
a) Naturally occurring substances but slightly different from hormones
b) Naturally occurring substances but less efficacious than hormones
c) Naturally occurring substances having the same structure but different pharmacological properties than hormones
d) Synthetic compounds, which resemble the naturally occurring hormones
d) Synthetic compounds, which resemble the naturally occurring hormones
- Regarding the mechanism of action of hormones, indicate the FALSE statement:
a) Hormones interact with the specific receptors in the wall of the cells
b) Cyclic AMP acts as a second messenger system
c) They stimulate adenylcyclase enzyme
d) Many hormones owe their effect to primary actions on subcellular membrane.
a) Hormones interact with the specific receptors in the wall of the cells
- Hypothalamic and pituitary hormones (and their synthetic analogs) have pharmacologic applications in three areas,
EXCEPT the following:
a) As replacement therapy for hormone deficiency states
b) As drug therapy for a variety of disorders using pharmacologic doses to elicit a hormonal effect that is not present at
physiologic a blood levels
c) As a diagnostic tool for performing stimulation tests to diagnose hypo- or hyperfunctional endocrine states
d) As food supplements
d) As food supplements
- Which of the following hormones is produced by the hypothalamic gland?
a) Growth hormone-releasing hormone (GHRH)
b) Follicle-stimulating hormone (FSH)
c) Aldosterone
d) Estradiol
a) Growth hormone-releasing hormone (GHRH)
- Which of the following hormones is produced by the anterior lobe of the pituitary?
a) Thyrotropin-releasing hormone (TRH)
b) Corticotropin-releasing hormone (CRH)
c) Growth hormone (somatotropin, GH)
d) Growth hormone-releasing hormone (GHRH)
c) Growth hormone (somatotropin, GH)
- The posterior pitutary does NOT secret:
a) Vasopressin
b) Oxytocin
c) Growth hormone
d) All of the above
c) Growth hormone
- Which of the following organs is a target for prolactin?
a) Liver
b) Adrenal cortex
c) Thyroid
d) Mammary gland
d) Mammary gland
- Which of the following organ hormones is a target for growth hormone (somatotropine, GH)?
a) Glucocorticoids
b) Insulin-like growth factors (IGF, somatomedins)
c) Triiodthyronine
d) Testosterone
b) Insulin-like growth factors (IGF, somatomedins)
- All of the following statements about growth hormone are true, EXCEPT:
a) It may stimulate the synthesis or release of somatomedins
b) Low levels of insulin-like growth factor (IGF)-1 are associated with dwarfism
c) Hypersecretion can result in acromegaly
d) It is contraindicated in subjects with closed epiphyses
c) Hypersecretion can result in acromegaly
- Correct statements about adrenocorticotropic hormone (ACTH) include all of the following, EXCEPT:
a) Endogenous ACTH is also called corticotropin
b) ACTH stimulates the synthesis of corticosteroids
c) ACTH is most useful clinically as a diagnostic tool in adrenal insufficiency
d) The oral route is the preferred rout of administration
d) The oral route is the preferred rout of administration
- The hypothalamic control exists for the thyroid gland. This consideration is:
a) True
b) False.
a) True
