1
Q
Class 1c Antiarrhythmic
A
Flecanide
Propafenone
2
Q
Class 1c Mechanism
A
Slows conduction Blocks open Na channels Dissociate slowly during diastole Effective at high heart rates “Use dependence”
3
Q
Class 1a antiarrhythmics
A
Quinidine
Procainamide
4
Q
Class 1b antiarrhythmics
A
Mexilitine
5
Q
Class III antiarrhythmics
A
Sotalol
6
Q
Class III mechanism of action
A
Blocks potassium channels
Prolonged depolarization
Prolonged action potential
Prolonged refractory period
“Reverse use dependence”
More effective at slower heart rates
Daily medication for maintenance of sinus rhythm
7
Q
Class 1b Mechanism if Action
A
Increase rate of depolarization
Increase delayed afterdepolarization
Shorten refractory period
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