Tissue
an aggregation of cells and extracellular substances
Epithelium
a tissue composed of closely aggregated cells with very little extracellular substance
Four basic types of tissues
epithelial tissue
connective tissue
muscular tissue
nervous tissue
surface or lining epithelia
epithelial cells form sheets that:
cover body surfaces
line luminal organs, tubular structures, and body cavities
glandular epithelia
secretory epithelia, their functions are synthesize, store and release its product
special epithelia
receptors for taste and hearing
Function: Protection
epithelium covering protects underlying tissue from mechanical abrasion/injury, harmful chemicals, invading microbes and from excessive loss of water
Function: Secretion
specialized to secrete specific chemical substances such as enzymes, hormones and lubricating fluids
Function: Absorption
lining of intestine absorb nutrients from digestion
epithelial cells of kidney tubules
Function: Diffusion
simple squamous epithelium promotes the diffusion of gases, liquids and nutrients
Function: Friction Reduction
smooth, tightly interlocking endothelial cells that line circulatory system reduce friction between blood and walls of blood vessels
Function: Cleaning
ciliated respiratory epithelium assists in removing dust particles from air passages
Function: Sensation
contain sensory nerve endings is found in the skin, ears and on the tongue
modified neurons in nose and eyes
ectoderm
epidermis of skin and its derivatives
mesoderm
comprised of mesothelium and endothelium
mesothelium
epithelium lining
THREE serous body cavities:
peritoneal, pleural, pericardial
endothelium
epithelium lining blood and lymphatic vessels and heart chambers
Endoderm
epithelial lining and glands most of the gastrointestinal tract and respiratory systems; liver; pancreas; urinary bladder
Epithelium Characteristics
covers surfaces and lines lumens may have specialization like glands high cellular density very little intercellular substance basement membrane present lining epithelium is avascular few nerve endings polarized, cohesive and closely associated to supporting CT
Mesenchymal Cell
lots of intercellular matrix
few cells
(connective tissue)
Hepatocyte
specialized epithelial cell
high cellular density
little intercellular matrix
Layout of Epithelial Cells
Apical (free) surface
lateral surface
basal surface next to basement membrane/lamina
nucleous close to basal lamina
Basal Lamina
when visible in light microscopy called basement membrane
interface of epithelial and connective tissue
selective barrier
provides structural support
formed by epithelial cells
Basement Membrane
basal lamina when this layer is visible with light microscopy
stains with PAS (periodic acid- Schiff) for carbs
semipermeable barrier