Cerebral perfusion pressure
=MAP - Intracranial cerebral pressure
MAP
1/3 systolic + 2/3 diastolic
Free water deficit
4 mL x weight (kg) x desired change in serum Na (meq/L)
Nitrogen intake
protein intake (g/day) x 0.16
Nitrogen balance
Nitrogen intake - Nitrogen lost
Polycythemia volume to be exchanged
[(observed Hct.- desired Hct (usually 55-60%) / observed Hct ] x infant’s blood volume (mL)
(blood volume = weight in kg x 80-100 mL/kg
Hardy Weinberg principle
p+q = 1
p2 +2pq + q2 = 1