Equations/Values

Question 1

Equation for amount of drug dose absorbed

Answer 1

(S)(F)(Dose)

Question 2

Equation for dose of different dosage form of same drug (i.e., IV to po switch)

Answer 2

[Amount (mg) absorbed from current form]/(S)(F) of new dosage form

Question 3

Equation for concentration in plasma (Cp)

Answer 3

(S)(F)(Dose)/(Vd)

Question 4

Equation for Loading Dose (LD)

Answer 4

(Vd)(Cp)/(S)(F)

Question 5

Equation for supplemental loading dose (LDsuppl.)

Answer 5

(Vd)(Cp_desired-Cp_initial)/(S)(F)

Question 6

Equation for Clearance (Cl)

Answer 6

[(S)(F)(Dose/τ)]/(Cp)

Question 7

Equation for Maintenance Dose (MD)

Answer 7

(Cl)(Cp)(τ)/(S)(F)

Question 8

Equations for rate constant (Kel)

Answer 8

• (Cl)/(Vd)
• (ln(Cp_t1) - ln(Cp_t2))/(t₂-t₁)

Question 9

Equation for Half-Life (t_1/2)

Answer 9

0.693/Kel

Question 10

What is normal concentration of saline (NaCl) solution?

Answer 10

• 0.9 % NaCl
• 0.9 g / 100 mL