The ESR is a non-specific marker of inflammation and depends on both the size, shape and number of red blood cells and the concentration of plasma proteins such as fibrinogen, alpha2-globulins and gamma globulins
does all of things cause high or low ESR
temporal arteritis
high
other factors which raise ESR: increasing age, female sex, anaemia
myeloma
high
SLE
high
infection
high
malignancies
high
polycythaemia
low
afibrinogenaemia/hypofibrinogenaemia
low
erythematosus
high