exam 2 Flashcards by Julie DiMuccio

Q

where does t cell development occur

A

thymus

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Q

where is the thymus

A

above the heart

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Q

goal of thymus

A

negative and positive select

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Q

the thymus positively select for

A

T cells that interact with self MHC protein (survivial)

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Q

the thymus negatively select for

A

T cells that bind self antigen (dearth)

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Q

the master regulator of T cell developement

A

Notch1

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Q

double negative makes

A

gamma delta t cells
lack cd4 and cd8

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Q

double positive makes

A

alpha beta T cells
expresses cd4 and cd8

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Q

single positive makes

A

cd4 or cd8

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Q

A

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