genotype vs phenotype
genotype: all of persons genes, inherited by biological parents
phenotype: persons observable characteristics and traits, combo of genes influenced by environment
cell parts and their connections
patterns of inheritance
AUTOSOMAL DOMINANT: 1 allele seen in phenotype, other silent. freckles, dimples, right handedness
AUTOSOMAL RECESSIVE: 2 silent alleles expressed. sickle cell anemia, left handedness
CODOMINANCE: 2 dominant alleles expressed, Blood type AB
INCOMPLETE DOMINANCE: Blend of 2 alleles expressed, hair colour or hair shape
Methods of studying heritability
TWIN STUDIES: compare phenotypes of monozygotic and dizygotic twins. if traits heritable, monozygotic will be more similar
ADOPTION STUDIES:child + biological parents vs adoptive parents. if heritable, similar to biological
TWIN-ADOPTION STUDIES: twins adopted into different households. if heritable, twins will be similar even if raised in different households
gene environment correlations
PASSIVE GENE ENVIRONMENT: characteristics of patent and child are similar
EVOCATIVE GENE ENVIRONMENT: characteristics of child evoke environments that support genetic traits
ACTIVE GENE ENVIRONMENT: child seeks environment or experience that supports genetic traits
Cell process of brain development
NEUROGENESIS: creation of new neurons from stem cells
CELL MIGRATION: migration of neurons from ventricular to sub ventricular zone to final home
SYNAPTOGENESIS: loss of synapse from lack of use or cell death
MYELINATION: formation of fatty sheath on neuronal axis to facilitate conduction of electrical signals
homozygous vs heterozygous
homozygous: same alleles expressed trait
heterozygous: different alleles for each gene
twins
monozygote: identical, zygote splits in 2 during 1st days of pregnancy, same chromosomes
dizygote: fraternal, 2 eggs released and fertilized by different sperm, unique set of chromosomes
number of neurons
assembly of brain
when brain development happens
differentiation of neural tube
passive cell displacement
active neuronal migration
cell elaboration
synaptogenesis
visual cortex
shows earlier developmental landmarks than the frontal cortex such as in synaptic density
myelination and white matter
myelination
myelination development
neural development
brain stem
cerebellum
occipital lobe