Exam 3 Practice

Question 1

What does Caffeine and Cola do?

Answer 1

• Inhibits phosphodiesterase activity

Question 2

Aspartate is transaminated to _____ to get Glutamate

Answer 2

• Alpha-ketoglutarate

Question 3

What is the intermediate in the GP shuttle?

Answer 3

• DHAP

Question 4

What lipoprotein is reduced in the glycogen-phosphate shuttle?

Answer 4

• Coenzyme Q

Question 5

The conversion of NADPH to R5P is via

Answer 5

• Steroid hormones

Question 6

A deficiency of HGPRT results in

Answer 6

• Lesch-Nyhan Syndrome

Question 7

What is the inhibitor of the rate-limiting step in the PPP?

Answer 7

• NADPH

Question 8

What is the cofactor required by transketolase?

Answer 8

• Thiamine pyrophosphate (TPP)

Question 9

What is found in tea leaves?

Answer 9

• Theophylline

Question 10

Which of the following is a nucleoside?

Answer 10

• Adenosine

Question 11

What is NOT a function of nucleotides?

Answer 11

• Primary energy source

Question 12

What is the rate-limiting step of purine biosynthesis?

Answer 12

• PRPP glutamyl transferase

Question 13

What inhibits adenylsuccinate dehydrogenase?

Answer 13

-

Question 14

What is the end product of purine biosynthesis?

Answer 14

• Uric acid

Question 15

What is a precursor of both pathways?

Answer 15

• PRPP synthetase

Question 16

What is the N3 and N9 amino acid?

Answer 16

• Glutamine

Question 17

What amino acid is not part of P nucleotide biosynthesis?

Answer 17

• Glutamate

Question 18

What is the treatment for gout?

Answer 18

• Colchicine

Question 19

What is the precursor to gout?

Answer 19

-

Question 20

The rate- limiting enzyme in pyrimidine nucleotide biosynthesis

Answer 20

• Carbamoyle phosphate synthetase II (CPS-II)

Question 21

Which amino acid helps with the reaction to CP?

Answer 21

• Glutamine

Question 22

What inhibits CP-II?

Answer 22

• UTP

Question 23

What enymatic defect results in orotic anemia?

Answer 23

• OP transferase

Question 24

Which is not a KB?

Answer 24

• Alanine

Question 25

Where are ketones not used?

Answer 25

- The liver

Question 26

Statins inhibit

Answer 26

- HMG reductase

Question 27

What is ketoacidosis?

Answer 27

- Type I DM

Question 28

KB RL

Answer 28

- HMG synthase

Question 29

What increases glu flux?

Answer 29

- Ketogenesis

Question 30

A high insulin/glucagon ration results in

Answer 30

- Insulin secretion

Question 31

Core of lipoprotein

Answer 31

- Cholesterol ester

Question 32

Cholesterol carbons come from

Answer 32

- Acetyl-CoA

Question 33

Active vitamin cholesterol

Answer 33

- 1,25 cholecalciferol

Question 34

What is not a function of cholesterol?

Answer 34

- Energy substrate

Question 35

RL of cholesterol

Answer 35

- HMG-Co reductase

Question 36

Cholesterol takes place in

Answer 36

- Cytoplasm

Question 37

The rate-limiting step ending

Answer 37

- Mevalonic acid

Question 38

Rate-limiting step of bile acid production

Answer 38

- 7-alpha-hydroxylase

Question 39

RL process cholesterol

Answer 39

- AMP kinase

Question 40

Eicosanoid signal transduction

Answer 40

- G-protein

Question 41

Arachadonic acid

Answer 41

- Linoleic acid

Question 42

RL of eicosanoid

Answer 42

- Phospholipase A2

Question 43

Aspirin inhibits

Answer 43

- COX

Question 44

Housekeeping enzyme

Answer 44

- COX-I

Question 45

High amount in MI

Answer 45

- Thomboxane

Question 46

Endothelial cell vasodilation

Answer 46

- Prostacyclin

Question 47

Glycine and cholic acid

Answer 47

- Glycocholic acid

Question 48

Favism

Answer 48

- G6PDh

Question 49

Ketogenesis

Answer 49

- Prolonged starvation