Ezetimibe

Question 1

MoA

Answer 1

Inhibits the absorption of cholesterol by the small intestine.
Alternative to statin in familial and primary hypercholesterolaemia

Question 2

Ezetimibe + Statin

Answer 2

Increased risk of myopathy (rhabdomyolysis)

Question 3

Common SE

Answer 3

Asthenia
GI disturbances
Muscle complaints

Question 4

Ezetimibe + fibrates

Answer 4

Increased risk of gallstones.
Discontinue if gallstones develops