1
Q
For which cancers can oncogenes be associated with chromosomal translocations:
A
CML - chronic myeloid leukemia
B cell lymphoma
Oncogenes activated due to chromosomal translocations
2
Q
what is promyelocytic leukemia ?
A
rearrangement of the gene for RAR (nuclear transcriptional regulator)
makes it insentitive to retinoic acid which is essential for HSC differentiation
BMS2021 F
flashcards
Decks in class (4)
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