FFPE

Question 1

FFPE

Answer 1

Stands for Formalin-Fixed Paraffin-Embedded

It’s a common method used to preserve tissue samples for microscopic examination in laboratories, particularly in histopathology.

Question 2

The FFPE process involves two key steps:

Answer 2

1. Fixation: The tissue sample is immersed in a formalin solution, which crosslinks proteins and helps maintain the tissue’s structure.
2. Embedding: The fixed tissue is then dehydrated and infiltrated with paraffin wax, a waxy substance that provides support and allows for thin sectioning.