1
Q
What is their mechanism of action?
A
Lowers blood triglyceride by reducing the livers production of VLDL and by speeding up the removal of triglycerides from the blood.
2
Q
What are it’s indications?
A
Severe hypertriglycerideaemia (>10mmol/L or in those who cannot tolerate a statin.
3
Q
Give examples of fibrates?
A
Bezafibrate
Fenofibrate
Ciprofibrate
Gemfibrozil- do not use with statins as high risk of myopathy (rhabdomyolysis)
4
Q
What are interactions?
A
Renal impaired
Statins
Myopathy
Cardiovascular
flashcards
Decks in class (34)
# Cards
-
ACE inhibitors9
-
Angiotensin receptor blockers9
-
Hypertension13
-
Heart failure15
-
digoxin10
-
Antiplatelets- aspirin10
-
Antiplatelets- ADP-receptor antagonists11
-
Angina13
-
Nitrates9
-
Atrial Fibrillation12
-
Cardiovascular Disease risk assessment6
-
deep vein thrombosis6
-
Phosphodiesterase 5 inhibitor8
-
Statins14
-
Amiodarone17
-
VTE21
-
Warfarin16
-
Beta blockers10
-
CCB15
-
hyperlipidaemia6
-
Fibrates4
-
Bile Acid Sequestrants4
-
Nicotinic acid5
-
Acute Coronary syndrome10
-
Cardiac arrest1
-
Oedema4
-
Diuretics-LOOP12
-
Diuretics- thiazide, and thiazide-like12
-
Peripheral Arterial Disease11
-
STROKE AND TIA3
-
Stable angina4
-
HYPOTENSION;3
-
aldosterone antagonist4
-
Enoxaparin5
