Final- Beta Strep

Question 1

cause of post-partum infection and neonatal sepsis?

Answer 1

Beta strep (GBS)

Question 2

Name 3 other infections that beta strep (GBS) can cause

Answer 2

pneumonia
UTI's in pregnant and non-pregnants
septic arthritis
skin infections
meningitis

Question 3

frequency of GBS in US births

Answer 3

1.8-3.2/1000 live births

Question 4

screening protocol for GBS in pregnant women

Answer 4

All pregnant women should be screened at 35-37 weeks gestation for vaginal and rectal GBS colonization

Question 5

which pregnant women do not need to be screened for GBS?

Answer 5

Women who have given birth to an infant with GBS and women who have GBS isolated from urine during current pregnancy should receive intrapartum chemoprophylaxis and don’t need to be screened (obviously ;) )

Question 6

intrapartum treatment of GBS

Answer 6

intrapartum chemoprophylaxis should be given at time of labor or rupture of membranes for all pregnant women with identified GBS.

Question 7

Do women who are having a planned c-section need intrapartum chemoprophylaxis?

Answer 7

no

Question 8

Which pregnant women should receive intrapartum GBS chemoprophylaxis?

Answer 8

• have had previous infant with invasive GBS
• GBS bacteriuria during current pregnancy
• unknown GBS status
• delivery at or equal to 18 hours
• intrapartum temp > or equal to 100.4

Question 9

What is the recommended regimen for intrapartum antimicrobial prophylaxis for GBS prevention?

Answer 9

Initial dose: IV penicillin G, 5 million units

• additional 2.5 million units IV every 4 hours until delivery
• see notes for other options

Question 10

antepartum treatment of GBS

Answer 10

• in the absence of GBS UTI, do not give antepartum treatment
• women with GBS UTI should be treated according to current standards of care for UTIs during pregnancy

Question 11

alternative treatments protocols for GBS (have not beend studied FYI, but in notes)

Answer 11

• garlic clove in vagina at bedtime the night before GBS test
• correct vaginal pH to reduce colonization of gut
• boost immune system with echinacea, garlic, vit c, oregon grape, etc.
• tea tree oil diluted with olive oil suppository
• boric acid cap suppository