Anabolism
refers to the metabolic pathways that synthesize complex molecules from simpler ones, using energy
example: making glucose from photosynthesis; proteins from amino acids
- requires energy
catabolism
refers to the metabolic pathways that break down complex molecules to simpler ones, releasing energy
example: cellular respiration(breaking down glucose)
- gives off energy
what is metabolic rate affected by?
Eactivity= altered skeletal muscle activity- exercise needs energy
- food-induced thermogenesis- digestion, absorption and use of stores
201
How does size effect metabolic rate?
the bigger you get metabolic rate drops since you can store more energy than a smaller animal
when grouping organisms together what is the overall slope of the graph
0.75 .
what is mass-specific?
resting metabolic rate scale with mass
what certain factors affect muscles and the force/production of movement and how?
-# of muscle cells in the tissue
- length of the muscle
The force generated by any muscle will decrease with the speed of contraction
a muscle is a bundle of what?
muscle fibres
during growth what takes place inside the cell?
hundreds of myoblasts fish to form a long, multi-nucleate cell
muscle fibres are filled with bundles of
myofibrils
myofibrils consists of stacks of what?
alternating thick and thin filaments
how are the thick and thin filaments in a myofibril organized?
they are arranged along the length of the myofibril in sarcomeres, which are the functional unit of muscles
under a microscope myofibrils appear what?
striated
what are the thin filaments in a muscle?
what are the thick filaments in a muscle?
each myosin protein is a dimer of two polypeptides coiled around each other with a globular “head” at one end and a long helical “tail”
Each myosin head domain has?
ATP binding site: this is where ATP binds to the myosin head.
Power Stroke Mechanism: The myosin head undergoes a conformational change after the ATP is hydrolyzed into ADP and phosphate. This change moves the head in a way that pulls the actin filament toward the center of the sarcomere, known as the power stroke. After the power stroke, ADP and phosphate are released from the myosin head, resetting it for a new cycle of muscle contraction.
what is a crossbridge?
the interaction between an actin protein and a myosin head group
what is the key thing when thinking about contraction in the sliding filament theory?
actin filaments do not get shorter
myosin filaments do not get shorter
what get shorter is the length of the sarcomere
what is the sarcoplasmic reticulum?
explain how muscle contraction is activated?
when a signal is received the motor neurone
1. opens ca- channels through facilatated diffusion
what happens when the ca2+ enters the cytosol?
the force generated during a muscle contraction increases when the number of what?
crossbirdges formed on a sarcomere increase
the force generated by any muscle will decrease with speed of contraction TRUE OR FALSE?
true
( rapid contraction decreases # of cross bridges)
The force generated by any muscle will increase as you increase the number of muscle cells in the tissue?TRUE OR FALSE
TRUE( more muscles = more sarcomeres)