1) What is Akathisia
Inability to sit still or restlessness and is more common in middle-aged patients. Person will pace, rock while sitting or standing, march in place, or corss and uncross the legs. All of these repetitive motions have an intensity that is frequently beyond the explanation of the individual. In addition akathisia may be present as a primarily subjective experience without motor behavior. The subjective experience includes feelings of anxiety, jitterness, or inability to relax, which the individual may or may not be able to express. Most difficult acute medication-related movement disorder to relieve. Pathology may involve more than just extrapyramidal motor system. A number o medications used to reduce symptoms include beta-andrengeric blockers, anticholinergics, antihistamines, and low dose antianxiety agents. Physical and psychological stress appear to increase the symptoms and frighten pt. Risk factors for extrapyramidal symptoms (EPS) include previous episodes of EPS
2) What is Echoalia
Repetition of another’s words that is parrot-like and inappropriate
3) What is Referential Thinking
Belief that neutral stimuli have special meaning to the individual, such as the television commentator speaking directly to the individual.
4) Study extrapyramidal side effects of Antipyschotic medications and treatment for
5) Study Neuroleptic Malignant Syndrome
Develops from reaction to antipsychotic medications. Develop severe muscle rigidity with elevated temp and cascade of symptoms (within next 48-72 hrs) and include 2 or more of following: hypertension, tachycardia, tachypnea, diaphoresis, incontinence, mutism, leukocytosis, change in LOC, and lab evidence of muscle injury (incrase creatinine phosphokinase). Most imp aspect of nursing care is early symptom recognition, holding dopamine-blocking antipsychotics and supportive care. Carefully monitor I&O and electrolyte status. Treatment includes admin of dompamine agonist (bromocriptine) and muscle relaxants (dantrolene and benzodiazepine). Some pts see improvement with ECT. Treating temp a priority
6) Study Anticholinergic Crisis
Caused by overdose or sensitivity to drugs with anticholinergic properties. May result from OD of antimuscarinic drugs (atropine, scopolamine, or belladonna). Drugs prescribed in psychiatric setting include TCAand antipsychotics. May produce acute delirium or reaction resembling schizophrenia. Characterized by: elevated temp, parched mouth, burning thirst, hot dry skin, decreased salivation, decreased bronchial and nasal secretions, dilated eyes, increased HR, constipation, htn or hypotension. May be flushed and experience neuropsychiatric symptoms of anxiety (agitation, delirium, hyperactivity, confusion, hallucination, seizures). Typically self-limiting, usually subside within 3 days. After use of drug d/c, improvements generally follow with 24-36 hrs
7) Review the communication technique of Reflection
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8) Study the neurotransmitter-Acetylcholine
Primary cholinergic neurotransmitter. Greatest concentration in PNS. Provides basic synaptic communication. Important role in learning and memory; some role in wakefulness and basic attention; peripherally activates muscles and is major neurotransmitter of the ANS; involved in higher intellectual functioning and memory. Role in communicating emotional state
9) Review Diazepam and side effects
Side effects typically areise within 2-3 weeks after medication begins. Side effects include: appetite suppression, insomnia, irritability, weight loss, nausea, headache, palpitations, blurred vision, dry mouth, constipation, and dizziness. Some experience BP changes, tachycardia, tremors, irregular HR. Monitor height and weight in children Avoid in pts with Tourettes syndrome. Symptoms of OD include: agitation, chest pain, hallucination, paranoia, confusion, dysphoria, seizures with fever, tremor, palpitations, hypo-/hypertension, rashes, aggression, difficulty breathing, leg and abd pain. Toxic dose above 20 mg.
Study Clozaril (Clozapine) adverse effects
Study symptoms of Tardive Dyskinesia
Involves irregular, repetitive involuntary movements of mouth, face, tounge. Begin no earlier than 6 months after med began or when med is reduced/withdrawn. May be irreversible Prevention includes using lowest dose of typical antipsychs and usage of atypical antipsychs. Risk factors include: age over 50, female, affective disorder (depression), brain damage/dysfunction, increased duration of treatment, standard antipsych med
Review the medication Lithium
Gold standard in bipolar pharmacologic treatment; indicated for manic symptoms (rapid speech, flight of ideas, irritability, grandiose thinking, impulsiveness, and agitation). Also used as augmentation in pts with major depression that only partially respond to antidepressants. Actively transported across cell membranes and alters Na transport in nerve and muscle cells. Leads to increased storage of catecholapines, reduced dopamine, increased norepipinephrine, increased GABA activity, and increased serotonin sensitivity. Assess: mental status, sodium intake (decreased intake with decreased fluids can lead to lithium retention; increased sodium, fluids may decrease lithium retention)
Study Tricyclic Antidepressants and Serotonin Syndrome
Study herbal supplements and depression
Regulated like foods, not meds and exempt from FDA efficacy and safety standards. Often have adverse reactions and interact with Rx meds. St. John’s Wort (SJW) used for depression, pain, anxiety, insomnia, and PMS. Believed to modulate serotonin, dopamine and norepinephrine. Risk for developing serotonin syndrome increases with other serotonergic drugs. Should not be taken with antidepressants.
15) Study indication of use for Antipsychotics
Indicated for schizophrenia, mania and autism and to treat symptoms of psychosis (hallucinations, delusions, disorganized thinking, agitation, bizarre behavior)
Review what Oculogyric crisis
Muscles that control eye movement tense and pull eyeball so pt is looking at ceiling.
Review Clozaril (Clozapine) and monitoring of side effects
Review Disordered Water Balance
May go undetected for months or years. Ingesting large amounts of water over prolonged period leads to ccomplications such as: renal dysfunction, incontinence, cardiac failure, malnutrition, permanent brain damage. Can progress to water intoxication when kidney’s capacity is overwhelmed and serum sodium falls below 120 (Symptoms of muscle twitching, irritability; risk for seizures, coma, or death). Pts are “driven to drink” and may consume 4-10 L/ day. May drink from fountains, showers, or toilets. Frequent trips to bathroom. Responses to fluid restrictions: emotional, increased psychotic symptoms, irritability, lability. Caused by changes in sodium levels
Review Antipsychotic Drugs-first and second generation on page 353 (table
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Study Schizoaffective Disorder and Risk factors
Varying degrees of schizophrenia and mood disorders. Pts at risk for suicide. Pts with psychosis are increased risk with comorbid depression. Risk factors for suicide increase with use of alcohol/substances, cigarette smoking, previous suicide attempt, and hospitalization. Lack of regular contact may be long term risk.
Review Borderline Personality Disorder and wrist cutting
Pts with BPD are impulsive and may respond to stress by harming self. Self-harm is effort to self-soothe by activating endogenous endorphins. Linehan suggests Five Senses Exercise:
Study Paranoid Personality Traits
Traits are longstanding suspiciousness and mistrust of persons in general. Refuse to assume personal responsibility for feelings, assign responsibility to others, and avoid relationships in which they are not in control or lose power. Pts are suspicious, guarded and hostile. Actions of others misinterpreted as deception, depreciation, and betrayal. Often unforgiving and hold grudges. Distance self from others. Persistent ideas of self-importance and tendency to be rigid and controlled
Know the most common indicator for ECT:
Most effective treatment for sever depression, also used for mania, schizophrenia (when other treatments failed).
Know common aftereffects of ECT
Headache, nausea, muscle pain. Memory oss is long-term effect