1
Q
What are the 4 cell types in gastric pits and what do they each secrete?
A
- Mucus neck cells: secrete mucus
- Chief cells: produce pepsinogen
- Parietal cells: Make HCl and intrinsic factor (necessary for Vit B12 absorption
- Endocrine cells: produce gastrin
2
Q
What are the three components to the gastric mucosal barrier?
A
- Apical cell membrane and tight intracellular junctions relatively impermeable to abide
- Mucus layer
- High local bicarbonate concentrations secreted by surface epithelial cells
