First exam Flashcards

(61 cards)

1
Q

What is the general chemical formula for carbohydrates?

A

C(H2O)

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2
Q

What is a monosaccharide?

A

A simple sugar.

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3
Q

What is a disaccharide?

A

A carbohydrate composed of two monosaccharides.

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4
Q

What is a polysaccharide?

A

A long carbohydrate polymer formed of many monosaccharides linked together.

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5
Q

What is the structural difference between ⍺-glucose and β-glucose?

A

In ⍺-glucose the hydroxyl (-OH) group is point downward while the β-glucose hydroxyl is pointed upward.

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6
Q

Why are the differences between ⍺-glucose and β-glucose biologically significant?

A

⍺-glucose forms starch/glycogen (digestible for energy), β-glucose forms cellulose (structural, indigestible by humans)

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7
Q

How do the storage forms of glucose differ in plants (starch) and animals
(glycogen) in terms of branching and biological function?

A

Glycogen in animals is a more highly branched polysaccharide than starch in plants.

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8
Q

Why are lipids considered hydrophobic? How does their structure explain this
property?

A

Lipids are hydrophobic because molecularly they are not polar and therefore insoluble in water.

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9
Q

What is the structure and biological role of fat?

A

Structure: triglyceride. Role: energy storage, insulation, organ protection, and forming cell membranes.

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10
Q

What is the structure and biological role of phospholipids?

A

Structure: amphipathic. Role: forming the lipid bilayer of all cell membranes, providing a fundamental barrier for a cell’s interior and exterior.

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11
Q

What is the structure and biological role of steroids?

A

Structure: four-ring carbon skeleton. Role: signaling molecules that regulate a wide range of physiological processes and serve as key structural components of cell membranes.

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12
Q

What is saturated fatty acids?

A

Fats with single bonds between every carbon atom in their hydrocarbon chain. Usually solid at room temperature.

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13
Q

What is unsaturated fatty acids?

A

Fats containing at least one carbon-carbon double bond in their carbon chain. Usually liquid at room temperature.

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14
Q

Why do cis double bonds in unsaturated fatty acids introduce “kinks” into hydrocarbon chains?

A

The rigid, double bond prevents free rotation and forces the hydrocarbon chains to bend at a 30-degree angle.

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15
Q

What are the three subatomic particles of an atom, and where are they located?

A

Protons, neutrons, and electrons. Protons and neutrons are located in the atom’s nucleus, while electrons are found in the electron cloud.

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16
Q

How do atomic number and mass number differ?

A

Atomic Number: # of protons. Mass Number: # of protons and neutrons.

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17
Q

What is a covalent bond?

A

A chemical bond where two atoms share a pair of electrons (creates a more stable molecule).

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18
Q

What is an ionic bond?

A

A chemical bond where one atom transfers one or more electrons to another atom.

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19
Q

What determines whether a covalent bond is polar or nonpolar?

A

In a polar covalent bond the electron(s) is transferred. In a non polar covalent bond the electron(s) are shared.

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20
Q

What is a hydrogen bond?

A

A weak attraction between a hydrogen atom and a highly electronegative atom (like oxygen or nitrogen).

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21
Q

Why is a hydrogen bond weaker than a covalent bond?

A

Hydrogen bonds do not involve the sharing of electrons, therefore easier to break.

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22
Q

Why is water considered the “solvent of life”

A

Its polar molecular structure allows it to dissolve a wide range of substances.

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23
Q

What properties of water result from hydrogen bonding?

A

Cohesion, adhesion, high boiling point, high heat capacity, and strong surface tension.

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23
Q

What is an acid?

A

A substance that can donate a proton, accept electrons, or increase the hydrogen ion concentration in an aqueous solution. Has a pH < 7.

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24
What is a base?
A substance that can donate an electron pair, accepts hydrogen ions. Has a pH > 7.
25
What elements make up most living matter, and why are they so abundant?
Carbon (C), Hydrogen (H), Nitrogen (N), and Oxygen (O).
26
What are the three main components of a nucleotide?
A phosphate group, a pentose sugar, and a nitrogenous base.
27
What are purines any pyrimidines?
Two classes of nitrogenous bases that form the genetic code in DNA and RNA (adenine, guanine, cytosine, thymine, and uracil).
28
How are nucleotides linked together to form nucleic acids?
Phosphodiester bonds (covalent bonds formed via dehydration).
29
What is meant by the "directionality" of a nucleic acid strand?
The fixed orientation of a single nucleic acid strand.
30
Compare the structures of DNA and RNA.
DNA is a stable, double-stranded helix. RNA is a single-stranded molecule with a more fragile structure.
31
Why is complementary base pairing important for DNA repliciation and transcription?
It provides a mechanism for the accurate and faithful transmission of genetic information, minimizing errors.
32
What is the difference between the sugar found in DNA and that found in RNA?
RNA contains ribose which has a hydroxyl (-OH) group, while DNA contains deoxyribose (a sugar that lacks this hydroxyl).
33
What are the four groups attached to the central carbon of an amino acid?
Amino group (-NH2), Carboxyl group (-COOH), Hydrogen atom (H), and R-group (side chain).
34
What type of bonds links amino acids together in a protein?
Peptide bonds
35
Primary level of protein structure
The unique, linear sequence of amino acids linked by peptide bonds in a polypeptide chain.
36
Secondary level of protein structure
The local folded structures that form within a polypeptide due to interactions between atoms of the backbone.
37
Tertiary level of protein structure
The overall three-dimensional structure of a polypeptide
38
Quaternary level of protein structure
Formed by the assembly of two or more polypeptide chains into a single, functional complex.
39
What is the role of hydrogen bonding in ⍺-helices and β-pleated sheets?
They stabilize protein secondary structures.
40
How do hydrophobic interactions influence protein folding?
It causes non-polar amino acids to cluster together in the protein's interior, shielding them from surrounding water.
41
What types of bonds stabilize tertiary structure?
Ionic bonds, hydrogen bonds, and hydrophobic interactions.
42
What is protein denaturation, and what causes it?
The process in which a protein loses its three-dimensional structure, resulting in a loss of function. It occurs when non-covalent bonds are disrupted.
43
How do chaperone proteins assist in protein folding?
By binging to unfolded polypeptides, preventing misfolding.
44
What structural differences distinguish prokaryotic cells from eukaryotic cells?
Prokaryotic cells lack a membrane-bound nucleus and other membrane-bound organelles like mitochondria.
45
What does it mean that eukaryotic cells are compartmentalized?
Eukaryotic cells are organized into specialized, membrane-bound organelles and structures.
46
What is inside of a nucleus? What is it bound by? What structures are found outside of it?
The cell's genetic material in the form of DNA. The nucleus is bound by membranes. Cytoplasm, endoplasmic reticulum, Golgi apparatus, mitochondria, lysosomes, vacuoles, and vesicles are found outside of the nucleus.
47
What is the function of ribosomes?
Protein synthesis (protein creation).
48
What is the function of rough ER?
Transports, modifies, and packages proteins.
49
What is the function of smooth ER?
Synthesizes lipids and steroids, metabolizes carbohydrates, and detoxifies harmful substances.
50
What is the function of the Golgi apparatus?
To process and package proteins and lipid molecules.
51
What is the function of lysosomes?
The cell's "recycling" and "waste" disposal system.
52
What evidence supports the endosymbiotic theory of mitochondria and chloroplast origins?
The presence of unique DNA in mitochondria and chloroplasts.
53
What does the secretory pathway hypothesis propose?
Proteins destined for secretion are marked by an intrinsic "signal sequence".
54
What organelles are involved in the secretory pathway?
The Endoplasmic Reticulum (ER) and the Golgi apparatus.
55
What role does the nuclear pore complex (NPC) play in protein transport?
A highly selective, bidirectional gateway regulating the transport of proteins and RNAs between the nucleus and cytoplasm.
56
What is endocytosis, and what is its main function in the cell?
To transport large particles, fluids, and specific molecules, such as nutrients, hormones, and even viruses, into the cell.
57
What is exocytosis, and when does it occur?
The process by which cells transport substances out of the cell by using a membrane-bound vesicle that fuses with the plasma membrane and releases its content to the exterior.
58
What are the three main types of cytoskeletal filaments?
Microfilaments (actin filaments) , intermediate filaments, and microtubules.
59
What are the main functions of microtubules, actin filaments, and intermediate filaments?
Microtubules provide structural support, actin filaments maintain cell shape and perform cytokinesis, and intermediate filaments provide mechanical strength.
60