% of body weight thats water?
60%
ECF vol?
1/3 of TBW
ICF vol?
2/3 of TBW
ECF can be split into?
Interstitial - 3/4 ECF
plasma - 1/4 ECF
6 needs for fluid therapy
Ways to lose fluid?
bleeding, vom, dia, pooling in 3rd space, not having access to water
What is fluid resuscitation and when is it needed?
to re-expand intravascular volume
- from loss of vasomotor tone (vasodilation) - anaesthesia, anaphylaxis, sepsis, hypovolaemia
What is parenteral nutrition?
when cant provide enteral nutrition - mix of AA, conc dextrose, lipis
How can fluids be defined?
tonicity , reason for them (replacement / maintenance), what they contain
Two main different types of fluid?
Crystalloid - small paticals - electrolytes, glucose, buffers. can distribute rapidly among all fluid compartments
Colloid- contains larger particles so cant diffuse out, stay in vessels and increase COP so need smaller volume. Natural e.g is blood products
Differences in tonicity of fluid
Isotonic
Hypotonic - dilutes blood - fluid into cells
Hypertonic - concentrates blood - fluid out of cells (decrease oedema)
What section of fluid is lost with dehydration?
Interstitial (between 5-12%) Give fluid slowly over 24 - 48 hr so distributes
What section of fluid is lost with hypovolaemia?
Plasma - give fluid bolus rapidly
When giving fluids how do you calculate whats needed?
% lost
maintenance
ongoing losses
if an animal is 10% dehydrated how much fluid do you need to give them?
10% x body weight
What is calf maintenance vol?
100ml/kg/day
If an animal is acidotic how do you calculate the sodium bicarbonate needed?
base defecit = 30% of body weight x base excess = mmol/l of isotonic saline
BE = value on blood pathology
30%of BW as body is about 60 % water and about half is ECF which is the only part affected by changes in pH