Organisms that exhibit dimorphism and grow on Sabouraud’s medium (low pH):
Fungi
Type of agar used for most fungi?
Sabouraud agar
Organism that causes athletes foot (tinea pedis)?
Trichophyton
Which fungal infection leads to superficial skin disease?
Trichophyton
- Epidermophyton and Microsporum cuase dermatophytosis
- Tx w/ Griseofulvin
Which fungus causes cerebral/brain infarct?
MUCORMYCOSIS
- CRYPTOCOCCUS - may spread into the meninges and cause Cryptococcal Meningitis
- ASPERGILLUS - causes aspergilloma “fungus ball” in the lungs causing pulmonary infection in ppl with AIDS or have undergone organ transplant
- MUCORMYCOSIS - Pt’s w/ diabetic ketoacidosis, burns, or leukemia are particularly susceptible. It results in black, dead tissue in the nasal cavity and blocks the blood supply to the brain.
- Mucormycosis is found in blood vessels (endothelium) & is often related to diabetic pts
Aflatoxin is produced by what fungus?
Aspergillus
Cell immunity is most important for?
Intracellular parasite
Which one can be seen as an intracellular organism?
Histoplasmosis
- In infected tissues, yeast cells of Histoplasmosis are found within macrophages.
Disseminated fungi?
Histoplasmosis
- Yeast in macropages
- Bird-bat drooping, via respiratory droplets
- Different than the rest of them
Which pathogen causes granulomatous lesion in lung resembling TB, similar symptoms?
Histoplasmosis
What doesn’t give you granulomas?
Gonorrhea
- Histoplasmosis, M. Tuberculosis and Tertiary Syphilis are granulomatous (immune system walls off)
What does not cause a mucosal or epidermal rash?
Histoplasmosis
Avian/bird related fungi?
Histoplasma capsulatum
Most common cause of fungal meningitis?
Cryptococcosis
What is dimorphism in fungus?
Mycelium (mold) or as yeast
Which fungus are dimorphic?
- Histoplasma capsulatum
- Blastomyces dermatitidis
- Coccidioides immitis
- Sporothrix shenckii
- Candidas Albicans
What fungal organisms are found in the soil?
- Aspergillus
- Blastomycosis
- Coccidioides
- Cryptococcus neoformans
- Histoplasma
