H.pylori eradication
PPI + amoxicillin + clarithromycin/metronidazole
H.pylori eradication if pen-allergic
PPI + clarithromycin + metronidazole
PBC most sensitive + specific antibody
Anti-mitochondrial antibodies - M2 subtype (98%)
Other findings in PBC
Anti-smooth muscle (SMA) 30%
Raised IgM
Antibodies in Type I autoimmune hepatitis
ANA +/- SMA
Antibodies in Type II autoimmune hepatitis
Anti-liver/kidney microsomal type 1 (LKM1)
Antibodies in Type III autoimmune hepatitis
Soluble liver-kidney antigen
H.pylori stool/urea breath test - not within
2 weeks of PPI
4 weeks of Abx