Gastrulation

Question 1

Oct4 and Sox2 in ES cells

Answer 1

• activate own transcription
• during differentiation to mesoendoderm and neuroectoderm, they regulate each other negatively
  (graph)

Question 2

Bilaminar disk and primitive streak

Answer 2

• bilaminar : epi and hypo
• primitive streak: thickening streak, extending to center with node… creates a groove and then regresses, but leaves the node

Question 3

node

Answer 3

• where cells enter the embryo
• creates notochord first

Question 4

draw cells moving into node

Answer 4

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Question 5

draw depiction of notochord forming