What is a mutation
A permanent change in the DNA of an organism
What is a gene mutation
when a nucletodie isnt properly copied during transcription
What is a deletion
A base is completley lost
What is substition
one base in a gene is subsituted for another
it only affects one AA
What is a insertion?
Extra base is added into the gene which may be a repeat or a diffrent base
What are the 3 types of mutation
Subsituation
Deltions
Insertions
What causes sickle cell
Base subustion
Properties of sickle cell
Not carry oxygen effeinctlY
Block the smallest blood vessles
Descriptive detail of how sickle cell is caused
a change of one base in one codon changes a single AA in a chain of 147 AA