Generalities

Question 1

2 hormones that is secreted by the testes

Answer 1

Testosterone

Mullerian-inhibiting factor

Question 2

What enzyme converts testosterone to dihydrotestosterone?

Answer 2

5-a-reductase

Question 3

Absence of mullerian-inhibiting factor causes ____

Answer 3

Uterus
Cervix
Oviducts
Upper 1/3 of vagina

Question 4

Wolfian duct regress in the absence of ____

Answer 4

testosterone

Question 5

The presence of ___ chromosome is the single most determinant of sex

Answer 5

Y

Question 6

Mesonephric duct

Answer 6

Wolfian duct

Question 7

Paramesonephric duct

Answer 7

Mullerian duct

Question 8

Hypothesis wherein one X chromosome present in females is inactivated

Answer 8

Lyon hypothesis

Question 9

sex chromatin mass

Answer 9

barr body

Question 10

Found in nucleus of neutrophils in females

Answer 10

Drumstick appendages

Question 11

What is detected in hair root test?

Answer 11

Fluorescent body (Y body)

Question 12

Gold standard for sex determination

Answer 12

Karyotyping

Question 13

AOG where all embryos have bipotential gonads

Answer 13

4-6 wks AOG

Question 14

Cells that secrete testosterone

Answer 14

Leydig cells

Question 15

Cells that secrete antimullerian hormone

Answer 15

Sertoli cells

Question 16

AOG when testes descends through inguinal ring

Answer 16

7-9 mos AOG

Question 17

Sertoli cells develop at ___ wks

Answer 17

6-7

Question 18

Leydig cells develop at ___

Answer 18

8-9 weeks

Question 19

2 control mechanisms in devt if phenotypic sex

Answer 19

Classic endocrine mechanism

Local paracrine mechanism

Question 20

What hormone is required in the diff of external genitalia?

Answer 20

DHT

Question 21

Genital tubercle develops in to ___ tissue

Answer 21

erectile
M: glans penis, corpus cavernosum
F: clitoris, vestibular bulb

Question 22

Genital swelling in M fuse to form ___

Answer 22

scrotum and prepuce

Question 23

Genital swelling in F do NOT fuse but develop into…

Answer 23

labia minora

Question 24

Urogenital sinus in M develops into…

Answer 24

urethra

cowper’s and prostate gland

Question 25

Urogenital sinus in F develops into...

Answer 25

urethra lower 2/3 of vagina Bartholin's and Skene's glands

Question 26

Genotype for Turner syndrome

Answer 26

XO

Question 27

Short stature, ovarian dysgenesis, shield chest with widely spaced nipples, webbed neck, coarctation of the aorta

Answer 27

Turner syndrome

Question 28

Testicular atrophy, eunichoid body shape, tall long extremities, gynecomastia, female hair distribution

Answer 28

Klinefelter syndrome

Question 29

Genotype of Klinefelter syndrome

Answer 29

47, XXY

Question 30

2 barr bodies, menstrual irregularities and learning d/o's

Answer 30

Superfemale (XXX)

Question 31

Type of hermaphroditism with functional gonads

Answer 31

True hermaphroditism

Question 32

Genetic males with female phenotype

Answer 32

Male pseudohermaphrodites

Question 33

Causes adrenal androgen overproduction in the fetus

Answer 33

Congenital adrenal hyperplasia/ | 21 hydroxylase deficiency

Question 34

Sex determination established by genetic inheritance

Answer 34

Chromosomal/ genetic sex