genes Flashcards by Courtney Massah

Q

ALK

A

Receptor Tyrosine Kinase;

Lung Adenocarcinoma

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Q

BCR-ABL

A

Non-receptor Tyrosine Kinase;

CML, ALL

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Q

BCL-2

A

Anti-apoptotic molecule;

Follicular and Diffuse Large B-Cell Lymphoma

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Q

BRAF

A

Serine/ Threonine Kinase;

Melanoma, NHL, Papillary thyroid carcinoma, Hairy cell Leukemia

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Q

c-KIT

A

Cytokine receptor;

GIST gastrointestinal stromal tumor

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Q

C-MYC

A

TF;

Burkitt Lymphoma t(8,14)

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Q

HER2/neu (c-erbB2)

A

Receptor tyrosine kinase;

Breast and Gastric carcinomas

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Q

JAK2

A

Tyrosine kinase;

Chronic myeloproliferative disorders (PCV)

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Q

KRAS

A

GTPase;

colon cancer, lung cancer, pancreatic cancer

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Q

L-MYC1

A

TF;

Lung tumor

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Q

N-MYC

A

TF;

Neuroblastoma

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Q

RET

A

Receptor Tyrosine Kinase;

MEN2A & MEN2B, papillary thyroid carcinoma

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