___________produces four gametes having half the number of chromosomes present in the parent cell
Meiosis
_________leads to two daughter cells having the same number of chromosomes as the parent cell.
Mitosis
When a male possesses a phenotypic trait that he passes to all of his daughters and none of his sons, the trait is said to be X-linked________.
Dominant
Trait appears in every generation with no skipping
Autosomal dominant
Incidence of the trait is much higher in males than in females
X-linked recessive
Trait is passed from an affected man through all of his daughters and half of his sons.
X-linked recessive
Affected males transmit the trait to all of their daughters and none of their sons.
X-linked dominant
The parents of the affected child may be consanguineous.
Autosomal recessive
Trait characteristically appears only in siblings, not in their parents, offspring or other relatives
Autosomal recesssive
- What do p and q represent in the Hardy-Weinburg formula?
- What do p2, 2pq and q2 represent?
- Gene frequencies
- Phenotypes
What antigens are in the P1Pk system?
P1, Pk and NOR
- What antigens does a P1 + person have on their red blood cells
- What antibodies can they form?
- P1, P and Pk
- They will not make antibodies
- What antigens does a P2 positive person have on their red blood cells
- What antibodies can they form?
- P and Pk
- Anti-P1
- What antigens does a P1k positive person have on their red blood cells
- What antibodies can they form?
- P1, P1k
- Anti-P
- What antigens does a P2k positive person have on their red blood cells?
- What antibodies can they form?
- Pk only
- Anti-P (possibly anti-P1)
- What antigens does a p person have on their red blood cells
- What antibodies can they form?
- No P, P1 or Pk
- Anti-P, P1, Pk (Tja)
True or False: Cord blood cells are Le(a-b-)
True
In order to have Lewis antigens on the red cell, the individual must have the ____ and ____ gene.
Se (FUT2) and Le (FUT3)
Wiener makes me whine and you have to memorize this one!
R1-DCe
R2-DcE
Ro-Dce
Rz-DCE
_r’-dCe
-r‘’-dcE
-r-dce
-ry-dCE
What is the relative order of frequency of the common Rh haplotypes in Whites and Blacks?
Whites-R1>r>R2>R0
Blacks-R0>r>R1>R2
R1 always >prevalence over R2
-Trait characteristically appears only in siblings, not in their parents, offspring or other relatives
-On average, one fourth of the siblings of the propositus are affected
-males and females are equally likely to be affected
Autosomal recessive
-Affected males transmit trait to all their daughters and to none of their sons
-Affected females who are heterozygous transmit the condition to half their children of either sex
-Affected females who are homozygous transmit the condition to all their children
X linked dominant
-Trait appears in every generation, with no skipping
-Trait is transmitted by an affected person to half the children on average
-Unaffected persons do not transmit the trait to their children
-males and females equally likely to have or to transmit the trait
Autosomal dominant
-Incidence of the trait is much higher in males than in females
-Trait is passed from an affected male through all his daughters to half of their sons
-Trait is never transmitted directly from father to son
-Trait may be transmitted through a series of female carriers; if so the affected males may skip generations
X-linked recessive
