genetics

Question 1

genetic defect in huntingtons

Answer 1

CAG repeat coding for poly-glutamine

Question 2

effect of poly-glutamine

Answer 2

toxic effect on cells causing neuronal loss

Question 3

what is anticipation

Answer 3

more repeats as it is passed down generations

worse condition as gets passed down

Question 4

when are symptom onset for huntingtons

Answer 4

adulthood

Question 5

what happens to brain structure in Alzheimer’s disease

Answer 5

brain atrophy
enlarged ventricles
shrinkage of hippocampus