Genome Replication and Expression

Question 1

3 types of microtubule in the mitotic spindle

Answer 1

• Aster microtubules
• Kinetochore microtubules
• Interpolar microtubules

Question 2

What happens in prophase?

Answer 2

• Chromosomes condense
• Centrosomes move apart

Question 3

What happens in prometaphase?

Answer 3

• Nuclear membrane breaks down
• Spindle microtubules attach to kinetochores and move actively

Question 4

What happens in metaphase?

Answer 4

• Chromosomes align at equator
• Kinetochores from paired sister chromatids attach to opposite poles of spindle

Question 5

What happens in anaphase?

Answer 5

• Sister chromatids synchronously separate
• Kinetochore microtubules shorten
• Spindle poles move apart

Question 6

What happens in telophase?

Answer 6

• Chromosomes arrive at poles
• Nuclear envelope reassembles giving 2 new nuclei
• Nucleoli reappear - RNA synthesis begins
• Initiation of plasma membrane cleavage

Question 7

What happens in cytokinesis?

Answer 7

Contractile ring is formed and mediates division of cell in two

Question 8

What complexes are needed for splicing?

Answer 8

RNA-protein complexes (snRNP)

Question 9

What does alternative splicing of some genes allow?

Answer 9

Production of different mRNA strands from the same gene