Geriatric

Question 1

Three acetylcholinesterase inhibitors used in mild to moderate Alzheimer’s

Answer 1

donepezil
galantamine
rivastigmine

Question 2

MOA of memantine

Answer 2

NMDA receptor antagonist

Question 3

NICE recommend memantine for:

Answer 3

• moderate AD but cannot take AChE inhibitors
• add-on to AChE inhibitors in patients with moderate or severe AD
• monotherapy in severe AD

Question 4

MMSE score - mild impairment

Answer 4

20 - 24

Question 5

MMSE score - moderate impairment

Answer 5

13 - 20

Question 6

MMSE score - severe impairement

Answer 6

<12

Question 7

Lewy Body dementia, core clinical features

Answer 7

fluctuating cognition
visual hallucinations
parkinsonism

Question 8

Pharmacological management of Lewy Body dementia

Answer 8

AChE inhibitors or memantine