Geriatrics

Question 1

What are microscopic findings in Alzheimer’s Dz?

Answer 1

Neurofibrillary tangles

B-amyloid protein plaques

Question 2

What are three gene’s associated with Alzheimer’s Dz?

Answer 2

Amyloid precursor protein gene at Chromosome 21
Presenilin-1 gene at Chromosome 14
Presenilin-2 gene at Chromosome 1

Question 3

What type of medication is used to treat Alzheimer’s? Name two.

Answer 3

Acetylcholinesterase inhibitors

Rivastigmine
Donepezil

Question 4

What test is commonly done to assess cognitive function? And what do the scores indicate?

Answer 4

MMSE

Severe <9
Moderate 10-18
Mild 19-24
Normal > 27