Gastroenteritis
gastroenteritis- 2 viral causes
Gastroenteritis- 2 bacterial causes
Jejuni and salmonella.
E coli
-Due to contaminated food.
Intestinal obstruction is common where in intestine
Signmoid colon.
Ileus
Gluten sensitive/celiac
Type 4
Atrophy of mucosal villi = decrease nutrient uptake.
Chronic fatigue, weight loss, anemia.
Increased risk of intestinal lymphoma.
IBS
-What kind of disorder
Functional disorder, no pathologic findings. Autoimmune.
Recurrent
Tx with increased fiber, exercise, stress reduction.
Two forms of IBS
Chrons and ulcerative.
Chrons
Granuloma inflammaton
Deep, across wall, skip lesions.
Anywhere in GI tract
Ulcerative colitis
Diverticulosis
More common in western countries with low fiber diet, decreased activity/obesity.
Blind pouch that develop in weak spots of wall.
Most asymptomatic, usually in sigmoid colon
Acute appendicitis.
10% of pop. Teens and males.
Right lower quadrant pain
Obstruction= pressure increases= blood flow hindered= edema, ischemia, necrosis and bacterial overgrowth. May rupture and cause peritonitis.
What can cause peritonitis (2 groups)
1. Infectious Ruptured appendix Bowerl perforation Ascites- excess fluid in abdomen Salpingitis- inf of fallopian tubes.
Colorectal cancer is the 2nd leading cause of
Cancer deaths.
Risk factors for colorectal cancer
Age
genetics
men= women
DIET high protein and fat, low fiber.
2 forms of polyps
2. Pedunculated polyp. long narrow stalk.
Adenocarcinoma arises from
Colonic adenoma
If there is intestinal bleeding, assume __ until proven otherwise
Cancer.
Carcinoembryonic antigen (CEA)
Serum tumor marker for colorectal carcinoma. Tumor specific antigen
Monitors cancer treatment, not a useful screening test. Because it is rarely elevated when the cancer is at a curable stage. Can also be produced by other cancers.
Familial adenomatous polyposis
Gardner syndrome.
Autosomal dominant- APC gene
Polyps develop in teen years, colon cancer by 30s.
Treat with surgery.
Familial adenomatous polyposis/Gardner Syndrome ocular assocaitions
Bear tracking from CHRPE.
Multiple and bilateral? Def ask about colon cancer. !!!