GI Flashcards

(38 cards)

1
Q

small left colon associations

A

maternal diabetes
maternal hypothyroidism
maternal toxemia
prematurity

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2
Q

intestinal structures due to NEC most common location

A

left colon

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3
Q

SIP risk factors

A

indomethacin
post-natal steroids
vasopressors
mechanical vent+ surf
maternal chorio

most common site is terminal ileum

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4
Q

parts of digestion that are well developed in a newborn

A

salivary amylase and lingual lipase - mouth for starch and fat digestion

gastric lipase

disaccharidases in small intestine (besides lactase 36wks)

everything else decreased

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5
Q

48 hrs of NPO causes

A

deceased villi length
decreased cell growth
increased apoptosis

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6
Q

trophic feeds cause

A

increased blood flow
increased barrier defenses
increased hormone regulation
increase motility

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7
Q

first sucking is present at

A

16 wks

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8
Q

most common type of TEF

A

Esophageal atresia with distal fistula

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9
Q

duodenal atresia has high rate of associated disorders they are -

A

trisomy 21
malroation
CHD
esophageal atresia
GU anomalies
annular pancreas

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10
Q

duodenal atresia occurs by

A

failure of recannulization by 8-10 weeks

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11
Q

jejunal-ileal atresia

A

due to ischemic injury- either by anatomic crushing or meds like cocaine

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12
Q

associations with malrotation

A

CDH
abdominal wall defects
intestinal atresias
beck with-weidemann

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13
Q

CHD worse outcome if

A

Right sided
Liver in the hernia
Need for Ecmo
Require requires a patch
FI02 need on postop d30

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14
Q

Transition zone for hirschsprung

A

Rectodigmoid

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15
Q

Small left colon transition zone

A

Splenic flexure

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16
Q

Difference between Meconium plug and Meconium ileus

A

Meconium plug involves the colon and is due immaturity of the colon

Meconium plug involves the distal ileum and due to hyperviscous secretions causing obstruction

17
Q

Disorder of failure of the lateral cephalic folds to close

A

Pentology of Cantrell

18
Q

Pentalogy of Cantrell

A

Cleft sternum
Anterior midline diaphragmatic abnormality
Pericardial defect
Ectopic cordis
Upper abdominal omphalocele

19
Q

Failure of the lateral abdominal folds to close

20
Q

Failure of the caudal and lateral folds to close

A

Cloacal or bladder extrophy

21
Q

Gastroschisis-
Happens on what side
With - umbilical cord
Associated with -

A

Right side
Intact umbilical cord
Associated intentional anomalies , all have malroation
Associated with IUGR

22
Q

OEIS complex

A

Omphalocele
Extrohpy of bladder
Imperforate anus
Spinal deformity

23
Q

Age of onset of nec byGA

26 wks
>31
Term

24
Q

Short gut is better if

A

The ileum is intact, the ileocecal valve is intact to prevent bacteria overgrowth

25
Short gut is worse if
Colon is resected No valve +- 25 cm take Valve intact but 40 cm taken
26
Multiple hemangiomas or one single large rapidly, growing hemangioma like lesion can also have retroperitoneal or mediastinal vascular abnormalities leading to high output, cardiac failure, DIC and thrombocytopenia
Kasabach Merrit syndrome
27
Five reasons why premise get NEC
Loose tight junctions Thin goblet cells Few pants cells Decreased IgA Increase inflammatory cytokines Altered TLR4 signaling
28
String and Apple core signs
Pyloric stenosis
29
First sucking present
16
30
Normal gastric emptying at
32 wks
31
How do neonates have normal carb digestion
Normal glucoamylase, glucosidases, disaccharideases Normal absorption from active transport Colonic salvage pathway
32
Left sided free air and perinatal depression
Gastric perf
33
What percent of Meconium ileus will have cf
90 But only 10% of cf get a Meconium ileus
34
Hirchsprungs Affected relatives ? Timing
33% 8-10 wks neurocrest cell migration
35
Corkscrew on upper gi Whirlpool on us
Malroation + volvulus
36
Bell staging
1. Mild, suspected, AB, feeding intolerance. 2 a: mild minor, electrolyte abnormalities, pneumatosis on x-ray 2 b: + moderate lab changes , portal venous air 3a : severe , strong lab changes, peritonitis 3b: surgical
37
Term risk factors for NEC
Cong heart disease IUGR Polycythemia Sepsis NAS
38
Most common congenital abnormality of the G.I. track
Meckel diverticulum