Defensive factors of the stomach
Mucus, bicarbonate, blood flow and prostaglandins
H. Pylori is gram positive or gram negative bacillus?
gram negative bacillus
where does H.Pylori live?
lives between epithelial cells and the mucus barrier (therefore it escapes destruction by acid)
which kind of ulcers are more common among people with H.Pylori
Duodenal
what makes peptic ulcers worse?
NSAIDS, gastric acid, pepsin and smoking
Zollinger-Ellison syndrome
Acid producing tumor
3 ways anti-ulcer drugs work
-Eradicate H.pylori
-Reduce gastric acidity
Enhance mucosal defenses