GI

Question 1

5 GI alarm sxs…

Answer 1

dysphagia

Bleeds (hemeatemesis, melena)

anemia

CA sxs or hx

inadequate response to tx

Question 2

1st line tx for GERD with no alarm sxs

Answer 2

H2 blockers

Question 3

5 meds that can cause pill esophagitis?

Answer 3

bisphosphonates
Fe
nsaids/ASA
potassium
tetracycline

Question 4

Tx for esophagitis…

Answer 4

omeprazole (PPIs)

Question 5

instructions for PPIs…

Answer 5

take QAM 30 min before 1st meal

Question 6

d/c instructions for PPIs

Answer 6

taper (prevent rebound)

Question 7

how long for onset of action of PPIs?

Answer 7

3-5 days

Question 8

4 risks of PPIs…

Answer 8

malabsorption (Ca, Mg, B12, Fe)

osteoporosis/fx

c. diff/infx

kidney disease

Question 9

duration of PPI dosing…

Answer 9

lowest dose, shortest duration

Question 10

caution in Mg antacids…

Answer 10

renal insufficiency

Question 11

SE for Mg antacids

Answer 11

diarrhea

Question 12

SE for aluminum antacids…

Answer 12

constipation

Question 13

caution for sodium bicarb…

Answer 13

edema/cirrhosis/CHF/Renal impairment

Question 14

calcium carbonate risk…

Answer 14

hypercalcemia

Question 15

1st line tx for H. Pylori

Answer 15

PPI + Bismuth + Metro + tetracycline

Question 16

H. pylori can lead to what 3 complications if not eradicated?

Answer 16

PUD
IDA
malignancy

Question 17

when should PPIs be d/c before h. pylori testing?

Answer 17

1-2 weeks

Question 18

When should bismuth and abx be d/c before h. pylori testing?

Answer 18

4 weeks

Question 19

The below is a sign of what in PUD?

peritoneal signs

Answer 19

perf, penetration

Question 20

The below is a sign of what in PUD?

succession splash

Answer 20

obstruction

Question 21

3 meds + NSAIDs that complicate PUD

Answer 21

anticoags
ASA
steroids

Question 22

with PUD but need for NSAIDs, what can be given as an adjunct?

Answer 22

PPI

Question 23

This drug is used to prevent NSAID induced ulcers

Answer 23

misoprostol

Question 24

Dx study for PUD

Answer 24

EGD

Question 25

Best long-term tx for gastroparesis?

Answer 25

improved glucose control | small, frequent low fat, low residue meals

Question 26

Dosing strategy for metoclopramide...

Answer 26

lowest dose, shortest duration | risk of EPS

Question 27

Metoclopramide can be used for...

Answer 27

gastroparesis

Question 28

C/Is for metoclopramide

Answer 28

obstruction perf bleed

Question 29

Risks of ondansetron (3)

Answer 29

arrhythmia prolonged QT serotonin syndrome

Question 30

Cautions for promethazine/prochlorperazine

Answer 30

sedating drug-induced Parkinsonism

Question 31

What antispasmodic can be helpful for IBS?

Answer 31

dicycloamine

Question 32

Dicycloamine has ______ properties, and should be used with caution in elderly patients

Answer 32

anticholinergic

Question 33

This drug for IBS can be considered for a psychosocial tx and abd. pain tx

Answer 33

amitriptyline

Question 34

IBS-D tx...

Answer 34

eluxadoline

Question 35

The following meds can help/hurt constipation? antipsychotics antidepressants opiods

Answer 35

hurt

Question 36

Adverse effects of bulk-forming laxatives and tx...

Answer 36

flatulence, bloating Fiber + fluid

Question 37

which anti-constipation? opiod-induced constipation w/ advanced illness or non-cancer pain

Answer 37

methylnatrexone

Question 38

adverse reactions to anti-diarrheals (2)

Answer 38

ileus | toxic megacolon

Question 39

peptobismol is contraindicated in...

Answer 39

ASA allergy

Question 40

Tx for diverticulitis...

Answer 40

flagyl + cipro

Question 41

f/u for diverticulitis

Answer 41

colonoscopy 6-8 weeks after resolution

Question 42

tx for new IBD-UC

Answer 42

mesalamine

Question 43

acute IBD flare tx..

Answer 43

CS

Question 44

flagyl SE...

Answer 44

disulfiram rxn

Question 45

perianal crohn dz tx...

Answer 45

cipro + flagyl