Upper gastrointestinal bleeds
Esophagus, stomach, duodenum
Esophageal varices
Abnormally enlarged veins, in submucosa of lower esophagus
Related to high pressure in liver causing dilation and ultimately rupturing
Esophageal varices: what do the red streaky marks indicate
Greater risk of rupture
Esophageal varices: warning signs
There aren’t really any until they rupture
Esophageal varices: risk factors: liver cirrhosis
-Increases pressure
-damage liver produces less clotting factors which increases the risk for bleeding
Esophageal varices: risk factors: alcohol
GI irritant
Esophageal varices: risk factors
-spicy food
-older age
-liver infection
-anticoagulants
-NSAIDs/ASA
-steroids
Esophageal varices: risk factors: anticoagulants
Increase risk of GI bleed x12
Esophageal varices: risk factors: NSAIDs/ASA
Cause ulcers/bleeding
-block COX 1 degrading the protectant layer in the GI and ulcers form
Esophageal varices: risk factors: steroids
Prednisone
-weakens the protective lining of the GI tract
Esophageal varices: clinical manifestations
-hematemesis
-Melina
-changes in LOC
-weak peripheral pulses
-tachycardia
-hypotension
-decreased urine output
-shock
Esophageal varices: clinical manifestations: shock
Very severe cases
-need to loose 25% or 1 L for any s/s
How much blood loss needs to occur for significant vital changes
2L
Mallory
GI bleed resulting from a tear at junction of gastroesophageal from forceful vomiting or binge drinking
Risk factors for Mallory
Eating disorders like bulimia or alcohol
Symptoms of upper GI bleeds
Dark black stools, bright red blood vomit with clots
Diagnosis of upper GI bleed: endoscopy
Scope down throat
-sedative or hypnotic
Diagnosis of upper GI bleed: barium swallow
Ingesting chalky mixture to coat intestines to observe abnormalities or bleeding
-X-RAY
-pt kept awake
Diagnosis of upper GI bleed: less likely alternatives
CT and MRI
Diagnosis of upper GI bleed: can a scope be a treatment as well
Yes, if they discover a problem they can treat it using banding technique
Laboratory tests for upper GI bleed: blood
Type and screen
-will most likely need blood
-packed RBC
-rare: whole blood
Laboratory tests for upper GI bleed: liver function
Test for liver damage and dysfunction
Liver damage lab results:
ALT, AST, ALP, bilirubin all increase
Albumin decreases
Laboratory tests for upper GI bleed: CBC
Comparing hemoglobin to other tests if possible