GI immunity

Question 1

a Th0 in the gut that binds peptide/MHC in the presence of _____ only turns into a Treg (also called an iTreg)

Answer 1

TGFbeta

Question 2

A Th0 in the gut that binds peptide/MHC in the presence of TGfbeta and IL6 (due to damage) will turn into a ______

Answer 2

Th1, Th2, or Th17

Question 3

what genetic alleles do u have to have to be at risk for celiacs?

Answer 3

HLA-DQ2 and HLA-DQ8

Question 4

what is the epitope that is responded to in celiacs disease

Answer 4

gliadin alpha 1