GI Patho

Question 1

Bulemia

Answer 1

• Parotid enlargement due to nutritional dificiency

Question 2

Gardners Syndrome

Answer 2

• Intestinal polyposis, premalignant variant (adenomatous)
• Osteomas
• Usually have prophylactic colectomy

Question 3

Plummer-Vinson Syndrome

Answer 3

• Dysphagia from esophageal stricture or webs
• Iron deficiency anemia
• Atrophic glossitis, thinning of vermillion borders and leukoplakia
• Oral squamous cell carcinoma

Question 4

Sjorgen Syndrome

Answer 4

• Autoimmune destruction of exocine glands (salivary and lacrimal)
• Dry eyes and mouth
• More prevalent in women
• Increased risk of lymphoma
• Systemic disease
  
  • Fatigue
  • Arthralgia/Myalgia
  • Gland enlargement
  • Raynaud phenomenon
  • Vasculitis
  • Peripheral neuropathy
  • Oral changes (angular chelitis, bumps on corner of mouth)

Question 5

How can Sjorgen syndrome begin

Answer 5

• T cells react against some AG in gland, immune complexes form, gland is destroyed
• Genetic predisposition
  *

Question 6

Sjorgen Syndrome Treatment

Answer 6

• Supportive and system based
• Oral
  
  • Adequate hydration
  • Scrupulous dental hygeine
  • Cholinergic agents (stimulate saliva)
• Eye
  
  • Lubricating solutions
• Systemic
  
  • Steroids