GI-Pharm

Question 1

What are the H2 blockers?

Answer 1

• Cimetidine
• Ranitidine
• Famotidine

Question 2

When should H2 blockers be taken?

Answer 2

at night before bed (dont eat after)- they arent effective for post-prandial acid suppression

Question 3

What are the AEs of H2 blockers?

Answer 3

• CYP interactions (theophylline, diazepam, creatinine levels increased)
• antiandrogenic effects
• cross BBB (confusion, dizziness, etc.)

Question 4

What are the PPIs?

Answer 4

-omeprazole, lansoprazole, etc.

Question 5

How do bismuth and sucralfate work?

Answer 5

they bind to ulcers and provide physical protection to allow HCO3- to reestablish a pH gradient