glomerulonephritis lecture

Question 1

give examples of glomerular disease

Answer 1

• diabetic nephropathy
• glomerulonephritis
• amyloid/ light chain nephropathy
• transplant glomerulopathy

Question 2

what are the most common causes of end stage renal failure?

Answer 2

• diabetes (first)

- chronic glomerulonephritis (GN)

Question 3

what can acute glomerulonephritis cause?

Answer 3

-acute renal failure

Question 4

what is glomerulonephritis?

Answer 4

-immune mediates disease of the kidneys affecting the glomeruli

Question 5

what does a proliferative lesion and red cells in urine suggest?

Answer 5

-damage to endothelial or mesangial cells

Question 6

what does a non proliferative lesion and protein in urine suggest?

Answer 6

-damage to podocytes

Question 7

how is glomerulonephritis diagnosed?

Answer 7

clinical presentation
blood tests
kidney biopsy

examination of urine:

• urinalysis (haematuria, proteinuria)
• urine microscopy (RBC, RBC and granular casts, lipiduria)
• urine protein (creatinine ration/24 hour urine)