Glucagon

Question 1

Classification

Answer 1

Hormone (antihypoglycemic agent)

Question 2

Mechanism of Action

Answer 2

• Converts glycogen to glucose
• Inhibits glycogen synthesis
• Elevates BGL
• Increases cardiac contractile force
• Increased heart rate

Question 3

Indications

Answer 3

• Hypoglycemia
• Beta blocker OD

Question 4

Contraindications

Answer 4

• Hypersensitivity
• Pheochromocytoma
• Insulinoma

Question 5

Adverse Effects

Answer 5

• Nausea, vomiting
• Rebound hyperglycemia
• Hypotension
• Sinus tachycardia

Question 6

Administration

Answer 6

• Hypoglycemia (Adult): 1 mg IM/IV/IO/SubQ
• Beta blocker overdose (Adult): 2-5 mg IV/IO over 1 minute, second dose 10 mg IV if needed.