Locations of glucose transporters
GLUT1- most cells eg muscle cells
GLUT 2 - beta cells, renal tubules, hepatocytes
GLUT 3 - CNS, placenta
GLUT 4 - Muscle, Adipose tissue
Which glucose transporter function is affected by insulin
GLUT4
Effect of inslulin on GLUT4
Shifts it to the plasma membrane
Reduces GLUT4 exocytosis
Effects of increased levels of free fatty acids on glucose metabolism
Inhibits uptake of glucose by muscles
Stimulates hepatic gluconeogenesis