Gout

Question 1

What is the diagnostic criteria for gout?

Answer 1

hyperuricemia >6.8 mg/dL and symptomatic

Question 2

What NSAIDs have an FDA approval for gout?

Answer 2

Indomethacin, Naproxen, Sulindac
-Ibuprofen is used but does not have FDA approval

Question 3

What is the dosing of Colchicine for acute gout attack?

Answer 3

Day 1: 1.2 PO once, then 0.6 mg 1 hr later
Days 2+: 0.6 mg BID
*has to be renally adjusted

Question 4

What are the Uricosuric drugs (2nd line)?

Answer 4

probenecid